*****
Fundamentals of Biochemistry CH 369 - Spring 2012 *****
Instructor: David W.
Hoffman,
Associate Professor, Dept of Chemistry
& Biochemistry
Office hours: Mon 1-2
pm, Tues
& Thurs 7:30 - 8:30 pm, or by appointment, in Welch 4.230C.
Email:
dhoffman@mail.utexas.edu office phone:
512-471-7859
Class meeting: Tuesday &
Thursday, 6 pm - 7:30 am, in Welch
2.256
Unique number:
69516
Class web page:
http://hoffman.cm.utexas.edu/courses/index369_sp12.html
You may register for this course at the UT Extension web site. Register through UT Extension
Course description: This
is a one semester course that covers the major concepts in
biochemistry, including the types of biomolecules, protein and enzyme
structure, membranes, and metabolism. The course may be of
interest to students who are on a path toward a health related field,
or anyone interested in how living things work at the molecular level.
Textbook: "Essential
Biochemistry" by Charlotte Pratt & Kathleen Cornely.
I'm recommending the 2nd edition, there is also a first edition.
Computer access: There
will be a class web page, and some class notes will usually be posted
on the web page after each class. It will therefore be necessary
to have access to a computer and internet.
Textbook: "Essential
Biochemistry" by Charlotte Pratt & Kathleen Cornely.
I'm recommending the 2nd edition, there is also a first edition.
Class attendance will not
effect grades. However, I think it will be extremely difficult to do
well in the course without attending class regularly.
Exams will be given during the
regular class time. Plan to take the exams on the scheduled time. If
you need to miss an exam due to extraordinary circumstances, inform me
as soon as possible so that other arrangements may be made.
Schedule for Spring 2012
Tues Jan 24 Course organization;
chemical basis of life (Chapter 1)
class notes (PDF)
class notes (PPT)
Thur Jan 26
Aqueous chemistry (Chapter
2)
class notes (PDF)
class notes (PPT)
a few practice questions to try
(PDF)
Regarding solutions to practice
problems, I will be happy to discuss any
of the practice problems at the
end
of each and every class period.
Tues Jan 31 From genes to proteins
(Chapter 3 and 4)
class notes (PDF)
class notes (PPT)
Thur Feb 2
Proteins & protein structure (Chapter
4)
class notes (PDF)
class notes (PPT)
Tues Feb 7 Proteins & protein structure
(Chapter 4
& 5)
class notes (PDF)
class notes (PPT)
Thur Feb 9
Protein function (Chapter 5)
class notes (PDF)
class notes (PPT)
some practice exam questions
(PDF)
answers to some practice exam
questions (PDF)
Tues Feb 14 Mid-term
exam #1 (covers chapters 1, 2, 3, 4, 5)
Thur Feb 16
Introduction
to enzymes (Chapter
6)
class notes (PDF)
class notes (PPT)
Tues Feb 21 Enzymes, kinetics and inhibition
(Chapter
7)
class notes (PDF)
class notes (PPT)
enzyme practice questions
(PDF)
<==
Thur Feb 23
Lipids & membranes
(Chapter 8)
class notes (PDF)
class notes (PPT)
Tues Feb 28 Lipids & membranes
(Chapter 8 & 9)
class notes (PDF)
class notes (PPT)
Thur Mar 1
Membrane transport
(Chapter
9)
class notes (PDF)
class notes (PPT)
Tues Mar 6 Membrane transport, review
(Chapter
9)
class notes (PDF)
class notes (PPT)
lipid and membrane practice
questions
(PDF) <==
answers to enzymes
practice questions (PDF)
answers to lipid and membrane
practice questions (PDF)
Thur Mar 8
Mid-term
exam #2 (covers
chapters 6-9 of 2nd edition,
chapters 6-8 of 1st edition)
answers to exam 2 (PDF)
March 10-18 Spring break
Tues Mar 20 Introduction to carbohydrate metabolism
(Chapter
11-12)
class notes (PDF)
class notes (PPT)
Thur Mar 22
Glucose metabolism (Chapter 12,13)
class notes (PDF)
class notes (PPT)
Tues Mar 27 The citric acid cycle
(Chapter
14)
class notes (PDF)
class notes (PPT)
Thur Mar 29
Oxidative
phosphorylation (Chapter
15)
class notes (PDF)
class notes (PPT)
Tues Apr 3 Oxidative
phosphorylation (Chapter
15)
class notes (PDF)
class notes (PPT)
Thur Apr 5
Metabolism topics & review day
class notes (PDF)
class notes (PPT)
glycolysis, Krebs
cycle & oxidative phosphorylation practice questions
(PDF) <==
answers to some
of the practice questions (PDF)
practice exam 3 questions
(PDF) <==
answers to
practice
exam 3 questions (PDF) <== (with
answer to #13 fixed)
Tues Apr 10 Mid-term
exam #3 (covers
chapters 11-15 of 2nd edition,
chapters 9-12 of 1st edition)
==>
Exam 3 will be in Painter 4.42 (PAI 4.42) <==
exam 3 answers
(PDF)
Thur Apr 12
Photosynthesis
(Chapter
16)
class notes (PDF)
class
notes (PPT)
Tues Apr 17 Photosynthesis
(Chapter
16)
class notes (PDF)
class
notes (PPT)
Thur Apr 19
Lipid metabolism (Chapter
17)
class notes (PDF)
class
notes (PPT)
study questions for
photosynthesis & lipid metabolism (PDF)
Tues Apr 24 Nitrogen metabolism (Ch.
18).
class notes (PDF)
class
notes (PPT)
some nitrogen study questions
(PDF)
Thur Apr 26
Finish
metabolism, then DNA topics. (chapters
19-20)
class notes (PDF)
class
notes (PPT)
Tues May 1 Topics from chapters 20, 21, 22.
DNA replication, transcription, translation.
class notes (PDF)
class
notes (PPT)
the last study questions
(PDF)
Thur May 3
Review day.
class notes (PDF)
class
notes (PPT)
The
final exam is on Tuesday, May 8, from 6 to 9 pm, in the
usual place: Painter 4.42.
Final exam: Covers the
entire course, and is required. The date and time are set by UT
Extension, and appear on the UT Extension web page (see
"calendar").
Grading: Midterm exams
are
100
pts each; the final exam will be 160 pts.
Your grade will be based on the total points you earn on the midterm
exams, plus the final exam.
The final exam is required. Grades will
be as follows:
A 92 % of possible points ; A- 90%
of possible points
B+ 87% to 90% ; B 83% to 87% ; B- 80 to
83 %
C+ 77% to 80% ; C 73% to 77% ; C- 70 to
73 %
D+ 67% to 70% ; D 63% to 67% ; D- 60 to
63 %
F < 60 % of possible points
Incomplete grades will only be given in the case of truly extraordinary
circumstances.
Students with disabilities may request appropriate academic
accommodations from the Division of Diversity and Community Engagement,
Services for Students with Disabilities, 471-6259.
Regarding exam regrades:
I you believe there has been an error in grading your exam, I am
willing to consider re-grade
requests. Submit regrade requests in
writing
along with your graded exam; include a brief written description of the
grading
error. Re-grade requests should be submitted within one week of
when the exam is returned.
UEX Policy on Scholastic Dishonesty: In promoting a high standard of academic
integrity, the University
broadly defines scholastic dishonesty—basically, all conduct that
violates this standard, including any act designed to give an unfair or
undeserved academic advantage,
such as falsifying academic records, cheating, plagiarism, unauthorized
collaboration, collusion, misrepresenting facts (e.g., providing false
information to
postpone an exam, obtain an extended deadline for an assignment, or
even gain an unearned financial benefit). Any other acts (or attempted
acts) that violate the basic standard
of academic integrity (e.g., multiple submissions—submitting
essentially the same written assignment for two courses without
authorization to do so). Several types of scholastic
dishonesty—unauthorized collaboration,
plagiarism, and multiple submissions—are discussed in more detail on
this Web site to correct common misperceptions about these particular
offenses and suggest ways to avoid committing them. For the University’s official definition
of scholastic dishonesty, see Section
11-802, Institutional Rules on Student Services and Activities.
Miscellaneous stuff that may be useful:
my
handy vitamin review (PDF)
diagram of the EM spectrum (PDF)
I like to read daily science news at Science
Daily
Every day I look at Astronomy
Picture of the Day
Positive thought: Try to make the world a slightly
better place, one day at a time,
one person at a time.